Hyperbranched polymers for controlled release of cisplatin.
نویسندگان
چکیده
Hyperbranched polymers based on a polyether and polyester have been modified and used as macromolecular ligands for the anticancer drug cisplatin, giving controlled release of the drug over 7 days.
منابع مشابه
Gold and Iron Oxide Nanoparticle-Based Ethylcellulose Nanocapsules for Cisplatin Drug Delivery
The present study is aimed at the overall improvement in the efficacy, reduced toxicity and enhancement of therapeutic index of cisplatin. Nanocapsules of cisplatin containing ethylcellulose have been prepared using solvent evaporation technique under ambient conditions. The prepared nanocapsules were used for controlled drug release of anticancer agents with gold and iron oxide nanoparticles. ...
متن کاملGold and Iron Oxide Nanoparticle-Based Ethylcellulose Nanocapsules for Cisplatin Drug Delivery
The present study is aimed at the overall improvement in the efficacy, reduced toxicity and enhancement of therapeutic index of cisplatin. Nanocapsules of cisplatin containing ethylcellulose have been prepared using solvent evaporation technique under ambient conditions. The prepared nanocapsules were used for controlled drug release of anticancer agents with gold and iron oxide nanoparticles. ...
متن کاملMatrix Tablets: An Effective Way for Oral Controlled Release Drug Delivery
The purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. Matrix system was the earliest oral extended release platform for medicinal use. Matrix tablets are most commonly used methods to modulate the release profile of drugs. They are much desirable and preferred for such therapy because they o...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Dalton transactions
دوره 43 شماره
صفحات -
تاریخ انتشار 2008